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C2  ·  22 words

Vaccines in French

How an immune response is planned, tested and approved.

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From these 22 words, as many per round as you like — up to all of them: first what is due today, then new ones. First you choose, then you fill the gap, then you write it yourself. Mistakes come back again shortly.

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The fifth entry is le vaccin à vecteur viral, and the middle word looks like a term of art when it is in fact the plainest thing in the phrase. Latin vehere meant to carry, and its agent noun was vector, the one that carries. That is the whole of it: le vecteur and our own « vector » are a carrier and nothing more. What makes the word hard to hear plainly is where English has since put it. « Vector » belongs to the mathematics classroom, where it is an arrow with a length and a direction, and to public health, where it is the mosquito that brings the disease rather than the disease itself; both senses are loud enough that the vaccine sense reads as jargon borrowed from one of them. It is the other way round, and all three are the same plain word. Older than any of them, the same root lies under a few English words with no Latin about them at all — « way », « wagon » and « weigh », the last of which meant to carry before it meant to measure. So the entry names a vaccine whose instructions arrive in a borrowed cart.

The words

Noun (m) (12)

Grammar for these: Definite article: le, la, les · Indefinite article: un, une

l’adjuvantthe adjuvantNoun (m)C2
L’adjuvant ne protège pas, il réveille la défense.The adjuvant does not protect; it wakes the defences up.
le vaccin vivant atténuéthe live attenuated vaccineNoun (m)C2
Le vaccin vivant atténué garde un agent affaibli.The live attenuated vaccine keeps a weakened agent inside it.
le vaccin inactivéthe inactivated vaccineNoun (m)C2
Le vaccin inactivé demande souvent une seconde dose.The inactivated vaccine often calls for a second dose.
le vaccin sous-unitairethe subunit vaccineNoun (m)C2
Le vaccin sous-unitaire ne montre qu’un morceau de l’agent.The subunit vaccine shows only a fragment of the agent.
le vaccin à vecteur viralthe viral vector vaccineNoun (m)C2
Le vaccin à vecteur viral emprunte un virus comme transporteur.The viral vector vaccine borrows a virus to do the carrying.
le corrélat de protectionthe correlate of protectionNoun (m)C2
Le corrélat de protection permet de juger sans attendre une épidémie.The correlate of protection allows a judgement without waiting for an epidemic.
l’anticorps neutralisantthe neutralising antibodyNoun (m)C2
L’anticorps neutralisant empêche l’entrée dans la cellule.The neutralising antibody prevents entry into the cell.
l’essai de phase troisthe phase three trialNoun (m)C2
L’essai de phase trois compare deux groupes tirés au sort.The phase three trial compares two groups drawn by lot.
le taux de basethe background rateNoun (m)C2
Le taux de base dit ce qui serait arrivé sans vaccin.The background rate says what would have happened without any vaccine.
le calendrier des vaccinationsthe immunisation scheduleNoun (m)C2
Le calendrier des vaccinations change quand une recommandation change.The immunisation schedule changes whenever a recommendation changes.
le rattrapage vaccinalthe catch-up vaccinationNoun (m)C2
Le rattrapage vaccinal reprend ce qui a été manqué.Catch-up vaccination picks up whatever was missed.
le choix des souchesthe strain selectionNoun (m)C2
Le choix des souches se fait des mois avant la saison.Strain selection is done months before the season begins.

Noun (f) (10)

Grammar for these: Definite article: le, la, les · Indefinite article: un, une

la primovaccinationthe primary courseNoun (f)C2
La primovaccination pose la base, le rappel l’entretient.The primary course lays the foundation and the booster maintains it.
la réponse cellulairethe cellular responseNoun (f)C2
La réponse cellulaire dure souvent plus longtemps que les anticorps.The cellular response often lasts longer than the antibodies do.
l’efficacité sur le terrainthe real-world effectivenessNoun (f)C2
L’efficacité sur le terrain tient compte des oublis et des retards.Real-world effectiveness takes account of missed and late doses.
la manifestation postvaccinale indésirablethe adverse event following immunisationNoun (f)C2
Une manifestation postvaccinale indésirable se déclare même sans lien prouvé.An adverse event following immunisation is reported even when no link is proven.
la réactogénicitéthe reactogenicityNoun (f)C2
La réactogénicité décrit la fièvre et le bras douloureux des premiers jours.Reactogenicity describes the fever and the sore arm of the first few days.
la détection de signalthe signal detectionNoun (f)C2
La détection de signal compare le déclaré et l’attendu.Signal detection compares what is reported with what is expected.
la libération des lotsthe batch releaseNoun (f)C2
La libération des lots passe par un laboratoire indépendant.Batch release goes through an independent laboratory.
la couverture vaccinalethe vaccination coverageNoun (f)C2
La couverture vaccinale varie fortement d’une région à l’autre.Vaccination coverage varies widely from one region to another.
la baisse de l’immunitéthe waning of immunityNoun (f)C2
La baisse de l’immunité se voit sur les courbes avant les cas.The waning of immunity shows on the curves before it shows in cases.
la dérive antigéniquethe antigenic driftNoun (f)C2
La dérive antigénique rend le vaccin de l’an passé moins juste.Antigenic drift makes last year’s vaccine less accurate.

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